22 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Differential Diaqnoses ... #diagnosis #management ... #treatment #rheumatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
onset - Mostly ... within one hour or longer ... Disorientation, vertigo Diagnostic ... Cold #Urticaria #diagnosis ... #rheumatology #
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... screening for disease ... with established disease ... Avoid meds that ... #hematology
Eosinophilic Gastroenteritis: Treatment Options Based on Severity of the Disease
Mild:
 • Trial of PPI
 • Trial
Severity of the Disease ... Concern for HES: • Hematology ... consult for evaluation ... • Additional diagnostic ... Gastroenteritis #Treatment #management
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... AdultOnset #Stills #Disease ... #AOSD #rheumatology ... #diagnosis #management
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Disease Systemic ... lasting two weeks or longer ... #rheumatology # ... management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... SLE+++, Adult-onset ... Still disease, ... #management #treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
sJIA) • Adult-onset ... Still disease ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... Systemic late-onset ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology ... #Differential #Diagnosis
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... culture used to diagnose ... ankles, knees, fingers ... Gout #Comparison #rheumatology ... #Diagnosis