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product reactions stills syndrome treatment activation adult adultonset differential encephalopathy hemophagocytic hlh lymphohistiocytosis macrophage mas neurology onset polychondritis posterior pres
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... AdultOnset #Stills #Disease ... #AOSD #rheumatology ... #diagnosis #management
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Disease Systemic ... lasting two weeks or longer ... #AOSD #diagnosis ... #rheumatology # ... management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
sJIA) • Adult-onset ... erythematosus [SLE], AOSD ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... SLE+++, Adult-onset ... Still disease, ... #management #treatment ... #summary #rheumatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
resembles ARDS, onset ... Graft Versus Host Disease ... Borrellia (Lyme disease ... #Transfusions #diagnosis ... #management #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
by 24 hours or longer ... Shock, Autoimmune disease ... symptoms: Acute onset ... elevated white blood ... #management #neurology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
resembles ARDS, onset ... Graft Versus Host Disease ... Borrellia (Lyme disease ... #Transfusion #diagnosis ... #management #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... pulses, bruits, or blood ... Nervous System: • Onset ... episcleritis as well as inner ... #Rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Symptoms: • Sudden onset ... aorta) • Eyes • Inner ... /EGPA • RA Diagnosis ... Polychondritis #rheumatology ... #diagnosis #management
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