16 results
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... deposit and can activate ... ankles, knees, fingers ... Gout #Comparison #rheumatology ... #Diagnosis
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
pyrophosphatase activity ... and/or x-ray - CPPD ... #Disease #Signs ... #Symptoms #Pathophysiology ... #Diagnosis
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
and Management ... cases Clinical Signs ... years - May have signs ... /symptoms of active ... decreased reflexes Pathophysiology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
knees, shoulders Signs ... sx improve with activity ... • Ultrasound Diagnosis ... : CLINICAL DIAGNOSIS ... #management #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
) Pathophysiology ... deposit and can activate ... culture used to diagnose ... Deposition #Disease #Rheumatology ... #diagnosis #management
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Excessive glutamate activity ... of UMN and LMN signs ... by decreasing activity ... #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... Syndrome #TLS #diagnosis ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... Diagnosis via genetic ... absent NK cell activity ... #management #treatment ... #hematology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Tuberculosis Diagnosis ... assay (IGRA) • PPD ... Tuberculosis #TB #Diagnosis ... #Management #Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Tuberculosis Diagnosis ... assay (IGRA) • PPD ... Tuberculosis #TB #Diagnosis ... #Management #Treatment