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diagnosis hematology anemia causes hemolytic agglutinin disease extravascular intravascular thrombocytosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... uremic syndrome ... Autoimmune (AIHA)"Cold ... . primary cold agglutin ... Extravascular #Causes #differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
AIHA Primary Secondary ... Syndrome (CAS): ... nose, ears, or fingers ... younger pts) Differential ... #anemia #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Diagnosis Secondary ... iron deficiency, hemolysis ... inflammatory disorders (e.g ... Myelodysplastic syndrome ... #secondary
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