29 results
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
manifestations of Down syndrome ... • Brushfield spots ... iris (pigmented spots ... incurved fifth finger ... #Downs #Syndrome
Keratoconjunctivitis: Inflammation of the conjunctiva and cornea secondary to Adenovirus infection.
Photo credit, Josh Fierer, M.D.

Charlie Goldberg,
Photo credit, Josh ... Fierer, M.D. ... Images #Clinical #Ophthalmology ... #Photo #Keratoconjunctivitis
Important Causes of Diplopia 
TIER 1-CRITICAL
Basilar artery thrombosis, Botulism, Basilar meningitis, Aneurysmn
TIER 2-EMERGENT:
Vertebral dissection, Myasthenia gravis,
, Orbital apex syndrome ... tumor, Miller-Fisher ... syndrome, Multiple ... differential #diagnosis #ophthalmology
Acquired Immunodeficiency Syndrome (AIDS): Summary of Causes and Ocular Manifestations
 • Molluscum lesions
 • Eyelid Kaposi
Immunodeficiency Syndrome ... • Cotton wool spots ... Complications #ophthalmology
Horner's Syndrome: Loss of sympathetic nervous system input to (in this case) right eye. 
Note that
Horner's Syndrome ... Images #Clinical #Ophthalmology ... #Photo #Horners ... #Syndrome #Ptosis
Differential diagnoses for the neuro-ophthalmologic finding of diplopia.
Neoplastic: 
 • Intraorbital meningioma 
 • Pituitary adenoma
for the neuro-ophthalmologic ... GBS • Miller-Fisher ... syndrome • Orbital ... Diagnosis #Causes #Ophthalmology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
lesions in the inner ... retinal nerve fiber ... -> Cotton-wool Spots ... -> Elschnig's Spots ... pathophysiology #ophthalmology
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
Exudates • Nerve fiber ... -> Cotton-wool spots ... of VEGF causing fine ... Retinopathy #Diabetes #ophthalmology
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
Clubbing of the Fingers ... White Spots (Leukonychia ... nonuniform white spots ... Spots in the pattern ... seen in Reiter's syndrome
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... • Weakness: Starts ... death Miller Fisher ... associated with Miller Fisher ... Guillain #Barre #Syndrome