12 results
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
encephalomyelitis • MOG antibody-associated ... optica spectrum disorder ... BEE #Syndromes #neurology ... #inflammatory #differential ... #diagnosis
Platelet Disorders - Differential Diagnosis Framework

Qualitative Defects:
 • Adhesion
 • Aggregation
 • Secretion

Quantitative Defects:
 • Production:
Platelet Disorders ... - Differential ... Diagnosis Framework ... Environment-mediated - Antibody-mediated ... Diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... (CVID, WAS), (neurologic ... #Differential # ... #Workup #hematology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
or Anti-NucIear Antibody ... ANA ≠ Autoimmune Disease ... Lymphoproliferative Disorders ... ANA #patterns #rheumatology ... #diagnosis #differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... nose, ears, or fingers ... younger pts) Differential ... IgM Includes Disorders ... hemolytic #anemia #hematology
Rhombencephalitis
BACTERIAL
- Listeria (biphasic illness with bulbar dysfunction occurring later)
- Mycobacterium tuberculosis
- Pneumococcus
- Brucella
- Borrelia (Lyme Disease)
-
myasthenia, Miller-Fisher ... anti-ganglioside antibody ... Rhombencephalitis #Differential ... #Diagnosis #Causes ... #Neurology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... metabolic or endocrine disorders ... (to support a diagnosis ... laboratory #workup #diagnosis ... #testing #Rheumatology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bouts of HTN Diagnostic ... sclerosis, NMOSD, MOG antibody ... glycoprotein (MOG) antibody ... #management #neurology ... #differential
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
IBD, Whipple's disease ... syndrome - SLE Neurologic ... Antiphospholipid-antibody ... #joint #pain #differential ... #diagnosis #rheumatology
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
Hearing Loss - Differential ... Diagnosis Framework ... include a: • Neurologic ... Mitochondrial disorders ... #Diagnosis #otology