12 results
Acetaminophen toxicity
Emergency Department Workup and Management - Rumack Matthew Nomogram

#Diagnosis #Management #Toxicology #APAP #Acetaminophen #Rumack #Nomogram
Acetaminophen toxicity ... Diagnosis #Management #Toxicology ... #APAP #Acetaminophen ... Nomogram #Stages #Toxicity
Acetaminophen metabolism and factors affecting toxicity. 
GSH = glutathione 

#Acetaminophen #APAP #metabolism #toxicity #Toxicology #Pathophysiology #Overdose
Acetaminophen metabolism ... factors affecting toxicity ... glutathione #Acetaminophen ... APAP #metabolism #toxicity ... #Toxicology #Pathophysiology
Ethylene Glycol Toxicity

#Pathophysiology #Toxicology #EthyleneGlycol #Metabolism #Fomepizole
Ethylene Glycol Toxicity ... #Pathophysiology ... #Toxicology #EthyleneGlycol
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Cyanide Toxicity ... #Cyanide #Toxicity ... #Toxicology #Pathophysiology
Rumack-Matthew Nomogram for Acetaminophen Toxicity #Diagnosis #Management #Toxicology #RumackMatthew #Nomogram #Acetaminophen #Toxicity #APAP #ALiEM
Rumack-Matthew Nomogram for Acetaminophen ... Toxicity #Diagnosis ... #Management #Toxicology ... RumackMatthew #Nomogram #Acetaminophen ... #Toxicity #APAP
N-Acetyl Cysteine (NAC) Therapy Mechanism of Action: The non-toxic route of APAP metabolism gets saturated in
#Pathophys #Toxicology ... NAcetylCysteine #Acetaminophen ... #Toxicity #emDocs
Toxidromes Compared: Anticholinergic, Cholinergic, Opioid, Sympathomimetic, Sedative-Hypnotic

During your physical exam, look for evidence of some of
acute cholinergic toxicity ... Opioid toxicity ... #Diagnosis #Toxicology ... #Toxidromes #Comparison
N-Acetylcysteine (NAC) restores hepatic glutathione!
Found to have 21-28% reduction in mortality for acetaminophen-induced hepatic failure
The earlier
concentration of acetaminophen ... ANY overdose of acetaminophen ... ) #Diagnosis #Toxicology ... #Nomogram #Acetaminophen ... #Toxicity #APAP
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... LacticAcidosis #Toxicity ... #Toxicology #Diagnosis
Salicylate Toxicity - Diagnosis and Management

Clinical Findings
Pathophysiology
Workup
Treatment

By Stacy Marshall, MD

#Salicylate #Toxicity #Diagnosis #Management #Toxicology #Aspirin #Treatment
Salicylate Toxicity ... Clinical Findings Pathophysiology ... #Salicylate #Toxicity ... Diagnosis #Management #Toxicology