10 results
Salicylate Effect on Oxidative Phosphorylation (www.derangedphysiology.com)
#Pathophysiology #Toxicology #Toxicity #Salicylate #Aspirin #Oxidative #Phosphorylation
Salicylate Effect on Oxidative ... www.derangedphysiology.com) #Pathophysiology ... #Toxicology #Toxicity ... Salicylate #Aspirin #Oxidative
Ethylene Glycol Toxicity

#Pathophysiology #Toxicology #EthyleneGlycol #Metabolism #Fomepizole
Ethylene Glycol Toxicity ... #Pathophysiology ... #Toxicology #EthyleneGlycol
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Cyanide Toxicity ... #Cyanide #Toxicity ... #Toxicology #Pathophysiology
Toxidromes Compared: Anticholinergic, Cholinergic, Opioid, Sympathomimetic, Sedative-Hypnotic

During your physical exam, look for evidence of some of
acute cholinergic toxicity ... Opioid toxicity ... #Diagnosis #Toxicology ... #Toxidromes #Comparison
Acetaminophen metabolism and factors affecting toxicity. 
GSH = glutathione 

#Acetaminophen #APAP #metabolism #toxicity #Toxicology #Pathophysiology #Overdose
factors affecting toxicity ... APAP #metabolism #toxicity ... #Toxicology #Pathophysiology
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... LacticAcidosis #Toxicity ... #Toxicology #Diagnosis
Salicylate Toxicity - Diagnosis and Management

Clinical Findings
Pathophysiology
Workup
Treatment

By Stacy Marshall, MD

#Salicylate #Toxicity #Diagnosis #Management #Toxicology #Aspirin #Treatment
Salicylate Toxicity ... Clinical Findings Pathophysiology ... #Salicylate #Toxicity ... Diagnosis #Management #Toxicology
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
inactive form, via oxidation ... #Pathophysiology ... #Toxicology #NitrousOxide
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
Amiodarone Induced Lung Toxicity ... and masses, and exudative ... effusions • Acute toxicity ... • Chronic toxicity ... diagnosis #management #Toxicology
Metabolic Pathways of Toxic Alcohols 

Panel A shows the metabolic pathways of toxic alcohols. Alcohol dehydrogenase
catalyzes the first oxidation ... #Pathophysiology ... #Toxicology #ToxicAlcohols