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diagnosis rheumatology degenerative gout hemophagocytic hlh jointdisease jointpain lymphohistiocytosis management msk summary treatment
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... and can activate inflammatory ... Monarticular inflammatory ... Inflammatory Arthritis ... #Gout #Comparison
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
joint disease Inflammatory ... carries heat and looks ... #Degenerative #Comparison ... #Versus #MSK #JointDisease ... JointPain #Diagnosis #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... production of pro-inflammatory ... Auto-amplification loop ... Infections+++: Virus
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