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diagnosis neurology 21hydroxylasedeficiency 21ohd amyotrophic differential endocrinology genetics hypophosphatemia hypoxia lateral management neuromuscular pediatrics phosphate pulmonary respiratory sclerosis weakness
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal Cord ... Motor Nerves: ALS ... Neuromuscular junction ... poisoning, Scorpion sting
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... glands • Salt wasting ... Late (shock): cold ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... disrupt cellular function ... multiple spinal cord ... - Causes progressive ... - Further testing
Hypophosphatemia and Hypoxia - Pathophysiology ↓ Phosphate leads to ↓ red cell 2,3-DPG and a reduction
and Hypoxia - Pathophysiology ... impacts respiratory function ... is a cause of refractory ... phosphorus is seen in COPD ... patients with COPD
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