6 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Neutrophils - Low RBC Folate ... Myelodysplastic Syndromes Macrocytosis ... Rule out B12 and Folate ... #Macrocytosis # ... Algorithm #Causes #Hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Infiltration: • Hematologic ... and non-hematologic ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • B12/folate
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
of macrocytic anemia ... patients with macrocytosis ... but undiagnosed, folate ... #Diagnosis #Macrocytosis ... #VitaminB12 #Folate
Diagnosing Vitamin B12 and/or Folate Deficiency

It turns out that simply measuring serum levels of B12 or
Vitamin B12 and/or Folate ... levels of B12 or folate ... #VitaminB12 #Folate ... Deficiency #Diagnosis #Nutrition ... #Hematology #ComparisonTable
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
Etiologies of Folate ... have hemolytic anemia ... In addition, folate ... differential #diagnosis #hematology ... #nutrition
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
deficiency • Fanconi’s anemia ... Antibody-mediated hemolysis Nutritional ... Vitamin B12 • Folate ... Differential #Diagnosis #Hematology