22 results
Methylmalonic Acid and Homocysteine Levels in Vitamin B12 and Folate Deficiency
 • B12 Deficiency: MMA elevated,
and Folate Deficiency ... Homocysteine elevated • Folate ... #MMA #folate #deficiency ... #VitaminB12 #diagnosis ... #hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
and non-hematologic ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • B12 ... /folate/combined
Diagnosing Vitamin B12 and/or Folate Deficiency

It turns out that simply measuring serum levels of B12 or
and/or Folate Deficiency ... or folate is simply ... #VitaminB12 #Folate ... Deficiency #Diagnosis #Nutrition ... #Hematology #ComparisonTable
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypoproliferative Macrocytic Anemia ... • 812, Folate ... #Macrocytic #Anemia ... diagnosis #algorithm #hematology
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Anemia - Underproduction ... Iron deficiency anemia ... disease - Vitamin B12 ... and/or folate deficiency ... Underproduction #Algorithm #hematology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
of macrocytic anemia ... and a vitamin B12 ... elevated, but anemia ... but undiagnosed, folate ... #VitaminB12 #Folate
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
• Thiamine B1 ... • Riboflavin B2 ... paraesthesiae • Folate ... gestation • Vitamin B12 ... signs #symptoms #nutrition
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
deficiency • Fanconi’s anemia ... Antibody-mediated hemolysis Nutritional ... consumption • Vitamin B12 ... • Folate deficiency ... Differential #Diagnosis #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Neutrophils - Low RBC Folate ... - Low Serum B12 ... - Low Serum B12 ... and Folate Deficiency ... Algorithm #Causes #Hematology
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
Etiologies of Folate ... have hemolytic anemia ... In addition, folate ... differential #diagnosis #hematology ... #nutrition