7 results
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
• 812, Folate ... Deficiency • ... #Macrocytic #Anemia ... diagnosis #algorithm #hematology ... #workup
Diagnosing Vitamin B12 and/or Folate Deficiency

It turns out that simply measuring serum levels of B12 or
Vitamin B12 and/or Folate ... levels of B12 or folate ... Since folate is ... #VitaminB12 #Folate ... #Nutrition #Hematology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
of the initial work-up ... if vitamin B12 deficiency ... but undiagnosed, folate ... #VitaminB12 #Folate ... #AAFP
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
and non-hematologic ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • ... B12/folate/combined
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Algorithm - Iron deficiency ... Vitamin B12 and/or folate ... deficiency - ... Underproduction #Algorithm #hematology ... #differential #workup
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
Etiologies of Folate ... have hemolytic anemia ... In addition, folate ... differential #diagnosis #hematology ... #nutrition
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Diseases: • GATA2 deficiency ... • Fanconi’s anemia ... Antibody-mediated hemolysis Nutritional ... Vitamin B12 • Folate ... Differential #Diagnosis #Hematology