9 results
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
- Primary Thrombotic ... Diagnosis Table ... Thrombocytopenic Purpura ... (TTP) • Shiga ... #TMA #hematology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
- TTP VS HUS ... Often hard to differentiate ... thrombocytopenic #purpura ... #Comparison #Diagnosis ... #Table #Hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
TTP/HUS indicates ... thrombotic thrombocytopenic ... purpura/hemolytic ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... /Quantity: • Primary ... /HUS - Hemolytic ... Defects: • DIC, TTP ... #Differential #
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
thrombocytopenic purpura ... (TTP), Hemolytic ... uremic syndrome (HUS ... usually IgM) (e.g. primary ... Extravascular #Causes #differential
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Diagnosis Algorithm ... Abnormalities in primary ... Henoch Schonlein Purpura ... #Causes #dermatology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... to the differential ... glomerulonephritis; TTP ... = thrombotic thrombocytopenic ... #Algorithm #differential
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Petechiae • Purpura ... DDX: • TMA’s (HUS ... /TTP/DITMA) - ... /HUS > DIC • Severe ... Treatment: • Treat primary
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
necrosis) - Thrombosis ... Primary (essential ... Skin necrosis • Purpura ... Cryoglobulinemia • TTP ... , HUS and HIT