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diagnosis hepatology lfts liver transaminitis aflp aih autoimmune biliary causes chemistry cholangitis cirrhosis comparison dehydrogenase disease enzymes gap globulin hellp
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... specificity to elevated ... normal AST/ALT ... chemistry #diagnosis #differential
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... Cholestatic Pattern (ALP ... kwburak #LFTs #Elevated
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... specificity to elevated ... function may be abnormal ... #differential #
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... disease US — Normal ... • Alcoholic hepatitis
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Mild jaundice, Elevated ... to 10-20-fold elevation ... to 10-20-fold elevation ... hepatology #obstetrics #hepatitis ... #comparison #differential
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Dehydrogenase (LDH) - Differential ... upon damage • Normal ... Idiosyncratic LDH Elevation ... #differential #
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... IgG typically elevated ... upper limit of normal ... (rare) - IgG Elevation ... #Autoimmune #Hepatitis
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
tests algorithm ... magnitude of enzyme elevation ... ALP, alkaline phosphatase ... #Algorithm #Hepatology ... Liver #Enzymes #Differential
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
slightly elevated ... early on but elevated ... obstruction • ALP ... bile ducts Differential ... Diagnosis: • Viral hepatitis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... fluid (CSF) is abnormal ... AST ALT • Hypocomplementemia ... - interstitial keratitis
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