6 results
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... ) - Differential ... It can remain elevated ... Elevation: • ... #differential #
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Mild jaundice, Elevated ... to 10-20-fold elevation ... to 10-20-fold elevation ... obstetrics #hepatitis #comparison ... #differential #
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
body water in comparison ... osmolality helps to differentiate ... ADH release is also ... Circulating ADH ... volume; UNa is elevated
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
Normal or slightly elevated ... Mild-to-moderate elevation ... dehydrogenase (LDH ... WBC count and differential ... or may not be elevated
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
specificity to elevated ... Bilirubin - +/- elevation ... or amyloid: • Elevation ... muscle, Kidneys • LDH ... chemistry #diagnosis #differential
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... specificity to elevated ... Bilirubin - +/- elevation ... of Liver Enzyme Elevation ... muscle, kidneys • LDH