8 results
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Mild jaundice, Elevated ... to 10-20-fold elevation ... to 10-20-fold elevation ... obstetrics #hepatitis #comparison ... #differential #
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... ) - Differential ... RBCs, muscle, liver ... Elevation: • ... #differential #
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... kwburak #LFTs #Elevated ... Transaminitis #Algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... • Drugs • AIH ... #Diagnosis #Algorithm
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... specificity to elevated ... Enzyme Elevation ... #diagnosis #algorithm
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
specificity to elevated ... Bilirubin - +/- elevation ... Enzyme Elevation ... muscle, Kidneys • LDH ... chemistry #diagnosis #differential
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... magnitude of enzyme elevation ... normalised ratio; LDH ... LFTs #Abnormal #Algorithm ... #Enzymes #Differential
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
stores in the liver ... which drastically elevates ... NAD+ yielding NADH ... #diagnosis #differential ... #algorithm #management