11 results
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Mild jaundice, Elevated ... to 10-20-fold elevation ... to 10-20-fold elevation ... hepatology #obstetrics #hepatitis ... #comparison #differential
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
specificity to elevated ... Bilirubin - +/- elevation ... or amyloid: • Elevation ... of Liver Enzyme Elevation ... chemistry #diagnosis #differential
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... specificity to elevated ... Bilirubin - +/- elevation ... of Liver Enzyme Elevation
Causes of ST Segment Elevation - Differential Diagnosis Framework

STEMI:
 • Upsloping convex STE: "Pardee's sign" +
of ST Segment Elevation ... - Differential ... segment becomes elevated ... blocking drugs #STElevation ... #differential #
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Dehydrogenase (LDH) - Differential ... upon damage • Normal ... Idiosyncratic LDH Elevation ... #differential #
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... disease US — Normal ... • Alcoholic hepatitis
Algorithm for the Evaluation of Dysphagia:Oropharyngeal:
- Characterized by difficulty initiating swallowing and accompanied by choking/coughing, nasopharyngeal
Algorithm for the ... , soft palate (elevation ... suprahyoid muscles (elevate ... #Extraluminal #Algorithm ... #Differential #
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... IgG typically elevated ... upper limit of normal ... (rare) - IgG Elevation ... #Autoimmune #Hepatitis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
levels - Usually normal ... or slightly elevated ... Mild-to-moderate elevation ... WBC count and differential ... or may not be elevated
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... magnitude of enzyme elevation ... #Algorithm #Hepatology ... Liver #Enzymes #Differential