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diagnosis oncology hodgkins agglutinin cell comparison disease erythematosus gap globulin hemolytic lupus management paraproteinemias plasmacytoma protein proteingap rheumatology sle systemic
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
translocation • Types: Classification ... Extranodal disease: GI ... • Other hematologic ... #NonHodgkins #comparison ... #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
autoimmune disorder or lymphoid ... - Lymphoid Malignancy ... Viral Infection Clinical ... younger pts) Differential ... #hematology #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(HCV) • CLL & ... (-) hemolytic anemia ... due to cold IgG ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
- Clinical Presentation ... Weight loss • Anemia ... Workup: • Full ... Immunohistochemical studies (to differentiate ... #hematology #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... gastric tumors • Hematology ... anemia • Other ... Gap #ProteinGap #differential ... #diagnosis #hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Solitary Cell Plasmacytoma ... plasmacytoma) Clinical ... Less common - GI ... • No CRAB - no anemia ... #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... pericardial/abd GI ... (hypertension, lower ... lymphopenia, low PLT • Anemia
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