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diagnosis hematology causes hemolytic agglutinin algorithm disease disorders extravascular hemolysis intravascular monoclonal oncology paraproteinemias petechiae petechial platelet rash thrombocytopenia workup
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Sensitive Antibodies ... Donath-Landsteiner Antibodies ... • Symptoms of anemia ... younger pts) Differential ... #hematology #diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
usually IgG) (e.g. lupus ... (e.g. primary cold ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(-) hemolytic anemia ... due to cold IgG ... • Lupus anticoagulant ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Autoimmune Vasculitis (lupus ... Measurement of antinuclear ... Algorithm #Causes #dermatology ... #physicalexam
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... practices that could ... anti-phospholipid antibodies ... changes), high MCV anemia ... Causes #Workup #hematology
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