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diagnosis hematology causes algorithm disease hemolytic workup agglutinin ana arthritis cold elevatedmcv erythematosus extravascular hemolysis intravascular laboratory macrocytic macrocytosis monoclonal
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... B12 - Anti-IF Antibodies ... B12 - Anti-IF Antibodies ... • Small Bowel Disorder ... Algorithm #Causes #Hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Lymphoproliferative Disorders ... Kumfer @AnnKumfer #Antinuclear ... #patterns #rheumatology ... #diagnosis #differential
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Vasculitis - Collagen disorders ... Autoimmune Vasculitis (lupus ... Measurement of antinuclear ... Algorithm #Causes #dermatology ... #physicalexam
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Sensitive Antibodies ... Donath-Landsteiner Antibodies ... • Symptoms of anemia ... younger pts) Differential ... #hematology #diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
usually IgG) (e.g. lupus ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... anti-phospholipid antibodies ... changes), high MCV anemia ... #Differential # ... Causes #Workup #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
-C3 GN • Cast ... (-) hemolytic anemia ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... lymphopenia, low PLT • Anemia ... 1, SCL-70, RNP antibodies ... anticardiolipin antibodies
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... erythematosus (SLE) - Antinuclear ... double-stranded DNA antibodies ... the presence of anemia ... metabolic or endocrine disorders
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