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diagnosis hematology causes abnormal algorithm aptt coagulation prolonged vasculitis bleeding bruising classification disorders glomerulonephritis hemostasis monoclonal oncology paraproteinemias petechiae petechial
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... Purpura Anti-GBM antibodies ... Glomerulonephritis #Vasculitis #differential ... diagnosis #algorithm #rheumatology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... PT and the aPTT ... antiphospholipid antibodies ... Causes #diagnosis #differential ... #hematology #coagulation
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
antiphospholipid antibodies ... and aPTT 1. ... antiphospholipid antibodies ... Causes #diagnosis #differential ... #hematology #coagulation
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Amyloidosis and ... histiocytosis, and ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Autoimmune Vasculitis (lupus ... for hepatitis B and ... Algorithm #Causes #dermatology ... #physicalexam
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... selected cases: INR/PT ... function test, ANA ... anti-phospholipid antibodies ... Causes #Workup #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... lupus anticoagulant ... Willebrand syndrome • Lupus ... Bruising #Hemostasis #Differential ... #Diagnosis #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... rapidly progressing GN ... such as systemic lupus ... ) pattern: antibodies ... #diagnosis #rheumatology
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