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diagnosis differential erythematosus management antibodies antinuclear autoantibodies symptoms table syndrome associations diseases hematology neurology patterns summary algorithm antibody antineutrophil aortitis
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... (SLE), Sjogren's ... (SLE), Systemic ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... antibodies) • Systemic ... lupus erythematosus ... in drug-induced SLE ... antibodies #diagnosis #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... small vessels - ANCA-associated ... lupus erythematosus ... - Sjögren ... #Diagnosis #Rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... Anticoagulant (LAC) • Sjogren ... • Scleroderma (Systemic ... Vasculitis: P-ANCA ... perinuclear), C-ANCA
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
) ANA or Anti-NucIear ... (SLE), Sjogren's ... (SLE), Systemic ... : Lupus (SLE), Systemic ... #patterns #rheumatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’ ... : Pathogenesis and ... other autoimmune diseases ... lupus erythematosus ... (SLE) Signs /
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... purpura: strong sign ... , and SLE) • Urinalysis ... differential #diagnosis #rheumatology ... #classification
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
ANA - Non-specific ... Anti-SSB (La) - Sjogren's ... c-ANCA - Vasculitis ... granulomatosis p-ANCA ... diagnosis #table #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Butterfly rash, Vasculitis ... pain (20%) Renal disease ... #SLE #systemic ... erythematosus #signs
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... heart block • Sjogren ... #Lupus #Erythematosus ... diagnosis #rheumatology
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