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diagnosis differential joint management vasculitis ana antibodies approach causes classification disease effusions knee laboratory monoarthritis monoarticular oligoarthritis oligoarticular patterns physicalexam
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... assay (IFA) is the main ... SLE), Sjogren's Syndrome ... , Sjögren Syndrome ... ANA #patterns #rheumatology
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Fever/Chills/Joint pain ... Chikungunya - Herpes virus ... Seronegative Reactive Syndrome ... Effusions: - Hematologic ... differential #diagnosis #msk
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Crystal induced (Gout ... - Autoimmune Rheumatologic ... fever • Lyme • Gout ... #Diagnosis #MSK ... #rheumatology #
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint Pain ... spondyloarthropathies, lupus ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... erythematosus (SLE) - Antinuclear ... , and low back pain ... diagnosis #testing #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
tract: Abdominal pain ... purpura, joint & gut ... involvement, abdominal pain ... vasculitis • Cogan syndrome ... Differential #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... inflammation Others: • Lupus ... such as systemic lupus ... Vessels: Supply gut ... differential #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
ab • RF • Antinuclear ... Membranoproliferative GN ... phenomenon (16%) MSK ... Arthralgia and Arthritis ... #Rheumatology #
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
sex • Metabolic syndrome ... swelling, significant pain ... frequent attacks • Arthritis ... Dual-energy CT → MSU ... management #treatment #rheumatology
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