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diagnosis syndrome disease druginduced rheumatoid activation classification comparison cppd deposition dermatology differential gout hematology laboratory macrophage mas pseudogout pyrophosphate rheumatic
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Lupus (DIL): ... Constitutional symptoms, Arthritis ... , SCLE-DIL (terbinafine ... thiazidic, PPI, ACE, calcium-b ... #table #rheumatology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
Rheumatoid Arthritis ... pain / swelling ... imaging Treatment ... #diagnosis #management ... #rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
, SCLE-DIL (terbinafine ... thiazidic, PPI, ACE, calcium-b ... Workup: - ANA ... #DIL #rheumatology ... #management
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... crystals (gout) or calcium ... • Systemic lupus ... profile (e.g., calcium ... low back pain)
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... nonerosive inflammatory arthritis ... lower jaw Treatment ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
-1 and IL-6, leading ... erythematosus [SLE ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... vesicular eruption - Joints ... claudication, aortitis ... SLE) • Urinalysis ... differential #diagnosis #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
onset of swelling, pain ... Acute Pseudogout: Treatment ... with acute neck pain ... Deposition #Disease #Rheumatology ... #diagnosis #management
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
Management Summary ... deposition in joints ... swelling, significant pain ... frequent attacks • Arthritis ... #treatment #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Membranoproliferative GN ... Arthritis Malignancy ... Adenocarcinoma Treatment ... #Diagnosis #Management
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