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diagnosis differential joint workup ana approach classification disease laboratory management monoarthritis monoarticular oligoarthritis oligoarticular patterns polyarthritis rheumatic rheumatoid sjogrens syndrome
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... assay (IFA) is the main ... Kumfer @AnnKumfer #Antinuclear ... #patterns #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
noninflammatory Signs ... • SLE • Psoriatic ... #Diagnosis #MSK ... #rheumatology # ... Polyarthritis #Polyarticular
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
spondyloarthropathies, lupus ... Polyarticular (5 ... Chronic = RA, SLE ... #Joint #Pain #MSK ... #rheumatology #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... ) - Antinuclear ... double-stranded DNA antibodies ... , and low back pain
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... purpura: strong sign ... C-ANCA) pattern: antibodies ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... Membranoproliferative GN ... phenomenon (16%) MSK ... Arthralgia and Arthritis
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