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diagnosis differential vasculitis algorithm cryoglobulins glomerulonephritis hematology monoclonal oncology paraproteinemias progressive rapidly rpgn types
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... , Cryoglobulinemia ... Glomerulonephritis #Vasculitis ... diagnosis #algorithm #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia ... (e.g. systemic lupus ... diagnosis #types #classification ... #rheumatology # ... vasculitis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
& Cryoglobulinemic ... Autoimmunity: • -MM/WM: Vasculitis ... (Cryoglobulinemic ... to cold IgG • Lupus ... Paraproteinemias #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... ANCA +MPO) • Cryoglobulinemic ... such as systemic lupus ... differential #diagnosis #rheumatology ... #classification
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