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diagnosis differential classification algorithm druginduced glomerulonephritis hematology hypersensitivity management monoclonal oncology paraproteinemias progressive rapidly reactions rpgn sle types vasculitides
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... involvement: Anti-GBM Disease ... Glomerulonephritis #Vasculitis ... diagnosis #algorithm #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis and Vasculitides ... rapidly progressing GN ... Others: • Lupus ... such as systemic lupus ... differential #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Autoimmunity: • -MM/WM: Vasculitis ... to cold IgG • Lupus ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... reaction, Haemolytic disease ... glomerulonephritis, Systemic lupus ... #table #classification ... #comparison
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Workup: - ANA ... Evolution: Chronic disease ... #sle #comparison ... #table #rheumatology
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