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algorithm weakness management abg acid acidbase als amyotrophic base bloodgas chronic comatose diplopia disorders doublevision dysarthria fatigue gas generalized interpretation
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy • Central or peripheral neurologic disease
disease • Myasthenia ... gravis • Muscular ... Becker - Limb-girdle ... #differential # ... causes #neurology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
Causes of Peripheral ... Diagnosis Algorithm ... Gravis • Lambert-Eaton ... Peripheral #Weakness #Neurology ... #Causes
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Myasthenia Gravis ... Limb- proximal weakness ... life-threatening Differential ... #Gravis #diagnosis ... #management #neurology
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Generalized Weakness - Differential ... Diagnosis Framework ... NMJ disorder (Myasthenia ... #Diagnosis #causes ... #neurology
Diagnosis of Myasthenia Gravis - Physical Exam Maneuvers • Sustained lateral gaze for seconds to elicit
Diagnosis of Myasthenia ... ptotic eyelid will cause ... for fatigable limb ... #Gravis #PhysicalExam ... #neurology
Diplopia - Double Vision - Differential Diagnosis Algorithm Clinical Pearls: • Diplopia is almost always binocular. •
Double Vision - Differential ... • Neurologic ... • Myasthenia ... Neuromuscular Junction • Myasthenia ... #DoubleVision #Differential
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
- Causes progressive ... the limbs; (2 ... Escorial criteria uses ... conditions listed in differential ... Lateral #Sclerosis #neurology
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Eaton Syndrome, Myasthenia ... Gravis, Organophosphate ... #differential # ... diagnosis #neurology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... - Differential ... Pulmonary Disease Neurologic ... Parkinson's • Myasthenia ... Gravis Pharmacologic
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Diagnosis Framework ... Postsynaptic: Myasthenia ... Gravis - Lack ... of UMN/LMN signs ... #Diagnosis #neurology
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