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diagnosis differential rheumatology nephrology dermatology pharmacology sle algorithm erythematosus hematology hepatology medications renal secondary syndromes systemic vasculitis acute barre bee
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
and less common diseases ... diagnosis and treatment ... Inflammatory causes ... • Systemic lupus ... #neurology #inflammatory
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... cerebritis #diagnosis #management
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... PAN Pyoderma gangrenosum ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar rash ... Positive in 60-80% of cases ... life-threatening • Treatment ... Evolution: Chronic disease
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Discontinuation of causal ... Manifestations: Malar rash ... Usual therapeutic management ... Evolution: Chronic disease
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... Treatment: • ... #Systemic #Lupus ... #rheumatology #management
Etiologies of Peripheral Neuropathy • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism • Medication-induced: ART, Antibiotics,
Syphilis, Lyme disease ... Vasculitis, Sjogren's, Lupus ... Paraprotein-associated (POEMS syndrome ... differential #diagnosis #causes ... #neurology
Streptococcal Toxic Shock Syndrome (STSS) Complication of invasive GAS disease characterized by shock & MOF → occurs
of invasive GAS disease ... GAS in 30% of cases ... erythematous macular rash ... #STSS #treatment ... #management #diagnosis
Pharmacologic Treatment of Hypertensive Emergencies in Pregnancy Drug - Dose range - Onset/oeak/duration - Side effects -
Pharmacologic Treatment ... , tachycardia, nausea ... , hypotension, lupus-like ... syndrome - Nifedipine ... , hypotension, rash
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... mainly AQP4-lgG disease ... (AQP4-lgG disease ... disorders (Systemic lupus ... Manifestations #diagnosis #neurology
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