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diagnosis differential hematology management aafp acute adrenal aki algorithm b12 cobalamin deficiency disorders endocrinology folate folicacid gap globulin homocysteine hospitalization
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the evaluation ... the most likely cause ... recovery also causes ... of the initial work-up ... Homocysteine #Algorithm #Workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... Diagnosis and Workup ... changes), high MCV anemia ... - Bone marrow evaluation ... #Workup #hematology
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
e.g AEIOU ) or anuria ... urgent nephrology evaluation ... are caused by prerenal ... CONSIDER INTRINSIC CAUSES ... KidneyInjury #simplified #workup
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... decrease in most cases ... result in severe anemia ... immune hemolytic anemia ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... medications, pancreatic dysfunction ... Worsening macrocytic anemia ... wt loss • If anemia ... total body stores Evaluation
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
phlebotomy/ blood work ... during clinical evaluations ... prolonged rest can cause ... lying down and can cause ... Hospitalization #causes
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... and pernicious anemia ... • Autonomic dysfunction ... antibody that works
Primary Adrenal Insufficiency: • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
secretion because the dysfunctional ... aldosterone - Low in cases ... Insufficiency #Evaluation ... endocrinology #workup
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... Causes of Monoclonal ... Thalassemia, Sickle cell anemia ... • Other causes
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