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diagnosis allergy hypersensitivity reactions definitions evaluation hematology management perioperative preop preoperative proteins rheumatology risk stratification subtypes
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
conjunctivitis Type ... Mediator: IgM + IgG ... Immunological Mediator: IgG ... glomerulonephritis, Serum ... #Types #Classification
Types of hypersensitivity reactions Type I - lgE-Mediated, Within I Hour (Anaphylaxis) Type II - IgG or IgM
reactions Type ... II - IgG or IgM ... Complex-Mediated, 1-3 Weeks (Serum ... #Classification ... #Allergy #Diagnosis
Subtypes of Serum Proteins Pre-albumin (Transthyretin) Albumin Globulins • Alpha-1: Alpha-1 antitrypsin, Serum amyloid A, Ceruloplasmin, Corticosteroid-binding globulin (Transcortin),
Subtypes of Serum ... • Gamma: IgM, IgG ... Proteins #Subtypes #algorithm ... #classification ... #Types #hematology
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... • Serum IgG4 ... • Pancreas: Type ... Labs: - ↑ Serum ... complement • Classification
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
difficult airway - Allergies ... Performance thorough ... event, follow ACC algorithm ... or LV dysfunction ... What is the type
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