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allergy hypersensitivity reactions definitions evaluation management perioperative preop preoperative rheumatology risk stratification
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Mediator: IgM + IgG ... Immunological Mediator: IgG ... glomerulonephritis, Serum ... #Types #Classification ... #Diagnosis #Definitions
Types of hypersensitivity reactions Type I - lgE-Mediated, Within I Hour (Anaphylaxis) Type II - IgG or IgM
reactions Type ... II - IgG or IgM ... Complex-Mediated, 1-3 Weeks (Serum ... #Classification ... #Allergy #Diagnosis
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... • Serum IgG4 ... • Pancreas: Type ... complement • Classification ... -4 #IGG4 #Diagnosis
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
difficult airway - Allergies ... Performance thorough ... event, follow ACC algorithm ... What is the type ... stratification #diagnosis
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