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diagnosis differential anemia causes hemolytic management product reactions agglutinin cold dermatology disease immunecompromised immunocompromised petechiae petechial physicalexam rash transfusion transfusions
Complement Deficiency Testing Algorithm • Normal CH50 and AH50 AND High suspicion for complement deficiency •
Complement Deficiency ... Testing Algorithm ... deficiency • Low ... #Deficiency #Testing ... #Algorithm #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... bartonella (oroya fever ... Differential #Diagnosis #Algorithm ... #workup #hematology ... #testing
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Clotting factor deficiency ... Red Flags: • Fever ... : • Complete blood ... • Fecal occult blood
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Positive Coombs testing ... sensitize red blood ... temperatures by fixing complement ... Symptoms: High fevers ... hemolytic #anemia #hematology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... Periodontal Disease Complement ... Deficiency • ... Infection #Fever ... #Causes #Hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Crossmatch - involves testing ... S/sx: Fever, flank ... recipients w/ IgA deficiency ... false negatives on testing ... diagnosis #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... recipients w/ IgA deficiency ... Sx include: fever ... false negatives on testing ... diagnosis #management #hematology
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