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diagnosis dermatology rheumatology anemia causes hemolytic petechiae petechial rash agglutinin classification cold compared comparison disease erythemas erythematosus glomerulonephritis immunecompromised immunocompromised
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Glomerulonephritis #Vasculitis ... #differential # ... diagnosis #algorithm ... #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... cardiac valve, vasculitis ... bartonella (oroya fever ... #workup #hematology ... #testing
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH These rashes can be especially challenging and are associated with devastating differential
Purpuric Rashes- THE ALGORITHMIC ... ; however, an algorithmic ... petechiae/purpura with fever ... petechiae/purpura with fever ... #Diagnosis #Dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... Coronary arteries - Fever ... : • Fevers • ... against MPO • Complement ... #rheumatology #
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Diagnosis Algorithm ... Infection - Vasculitis ... Red Flags: • Fever ... #Causes #dermatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Positive Coombs testing ... younger pts) Differential ... Symptoms: High fevers ... hemolytic #anemia #hematology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... Diagnosis Algorithm ... Periodontal Disease Complement ... Infection #Fever ... #Causes #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... anti-Smith Ab, low complements ... permanent alopecia Differential ... to: Arthritis, Fever ... RNP antibodies, Complement
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
to heat (fires, heating ... pads, heating blankets ... of necrotizing vasculitis ... comparison #table #differential ... #diagnosis #dermatology
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