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diagnosis endocrinology insufficiency acth cushing differential syndrome
Cushing Syndrome Testing Algorithm INDICATIONS FOR TESTING: • Suspected Cushing syndrome (central obesity, muscle weakness, refractory hypertension) Testing:
Algorithm INDICATIONS ... Cortisol, Saliva • Low ... dexamethasone suppression test ... endocrinology #Adrenal ... #Hyperfunction
Diagnosis Adrenal Insufficiency - Algorithm Step 1) Screening Test: 6-8AM Cortisol Level - Early morning cortisol levels
Insufficiency - Algorithm ... Step 1) Screening ... specificity for AI (but low ... require Cosyntropin testing ... - Low ACTH is
Adrenal Insufficiency Differential Diagnosis Algorithm Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
, hypoglycemia Testing ... hormone (ACTH) stimulation ... test AND • Baseline ... plasma ACTH Low ... insufficiency • Low
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH Early am cortisol < 3
Diagnosis Algorithm ... then go to stim testing ... Standard Stim test ... primary AI - Low ... #ACTH #Stimulation
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