22 results
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
Features Required ... or hyporeflexia Features ... Elevated CSF protein Features ... spectrum disorders Features ... diagnosis #criteria #neurology
Fat Embolism Syndrome
Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
Fat Embolism Syndrome ... stabilization of fractures ... Pathophysiology ... Fat #Embolism #Syndrome ... #Diagnosis #Signs
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... Incr Skeletal fractures ... #genetics #pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... organ damage • Treatment ... : • Pathophysiology ... worrisome EKG features
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... acquired forms of haemophagocytic ... A subset of hemophagocytic ... Histopathologic features ... Treatment: • Corticosteroids
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... Overwhelming clinical syndrome ... Diagnosis: HLH signs ... • Bicytopenia Treatment ... • Supportive measures
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... Guillain-Barre Clinical Features ... demyelination features ... Treatment: • Plasmapheresis ... #neurology
PRES (Posterior reversible encephalopathy syndrome) - Features

#PRES #Posterior #reversible #encephalopathy #syndrome #Presentation #Symptoms #Signs #Diagnosis #Neurology
encephalopathy syndrome ... ) - Features ... encephalopathy #syndrome ... Presentation #Symptoms #Signs ... #Diagnosis #Neurology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... Carpal Tunnel Syndrome ... Acne • Coarse features ... Overproduction #diagnosis #signs ... endocrinology #pathophysiology
Parkinsons plus syndromes have features of parkinsonism but they differ from parkinsons disease in having some
Parkinsons plus syndromes ... have features of ... some additional features ... unresponsive to treatments ... #Diagnosis #Neurology