37 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... : • Pathophysiology ... worrisome EKG features
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... Incr Skeletal fractures ... #genetics #pathophysiology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... A subset of hemophagocytic ... cytokines, such as ... tests ↑ AST ↑ ALT ... Histopathologic features
Fat Embolism Syndrome
Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
Fat Embolism Syndrome ... stabilization of fractures ... Pathophysiology ... Fat #Embolism #Syndrome ... Diagnosis #Signs #Symptoms
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... Overwhelming clinical syndrome ... the disease is also ... HLH signs and symptoms ... TheIDtrivia #HLH #Hemophagocytic
Pediatric Inflammatory Multisystem Syndrome Temporally associated with SARS-CoV-2 infection (PIMS-TS)
Clinical features
all: fever > 101.3 F
most: oxygen
Inflammatory Multisystem Syndrome ... PIMS-TS) Clinical features ... all: fever > 101.3 ... #Inflammatory #Syndrome ... diagnosis #Signs #Symptoms
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... Carpal Tunnel Syndrome ... Acne • Coarse features ... diagnosis #signs #symptoms ... endocrinology #pathophysiology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... spine Signs / Symptoms ... • As soon as ... #MSK #pathophysiology ... #diagnosis #symptoms
Psychotic Disorders - Differential Diagnosis Algorithm

Mood disorder with psychotic features
 • Psychotic symptoms present exclusively during
with psychotic features ... • Psychotic symptoms ... during major mood syndrome ... • Psychotic symptoms ... also present outside
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• recurrent fractures ... adult population: also ... collection with EDTA Pathophysiology ... mineralization Symptoms ... pain - Frequent fractures