61 results
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Type I Hypersensitivity ... leading to an allergic ... Sensitization" to Allergen ... conjunctivitis • Anaphylaxis ... #TypeI #Type1
Drug Treatment of Anaphylaxis and Allergic Reactions
First-Line Therapy 
 - Epinephrine 
 - Oxygen 
 -
Drug Treatment of Anaphylaxis ... and Allergic Reactions ... Second-Line Therapy - H1 ... Prednisone #Anaphylaxis ... #Medications #Allergy
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Hypersensitivity: Summary Type ... conjunctivitis Type ... Graves' Disease Type ... Serum sickness Type ... #Types #Classification
Allergic Reaction Classification
Type 1 reaction: Acute anaphylactic reaction
Type 2 reaction: Cytotoxic reaction
Type 3 reaction: Immune complex
Type
Allergic Reaction ... Classification Type ... Immune complex Type ... delayed reaction #Allergic ... #allergy #diagnosis
Management of Anaphylaxis - Interventions
Epinephrine - Bolus, Infusion, Nebulized
Posture
O2
Fluids
Albuterol 
H1-Antihistamines, H2-Antihistamines
Glucocorticoids
Additional Vasopressor
Glucagon
Sugammadex
Methylene blue
Tranexamic acid
ECMO

#anaphylaxis #management #treatment
Management of Anaphylaxis ... Fluids Albuterol H1 ... Tranexamic acid ECMO #anaphylaxis ... Interventions #allergy
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... Local and systemic anaphylaxis ... hay fever, food allergies ... , and drug allergies
Types of hypersensitivity reactions

Type I - lgE-Mediated, Within I Hour (Anaphylaxis)
Type II - IgG or IgM
Types of hypersensitivity ... reactions Type ... Within I Hour (Anaphylaxis ... ) Type II - IgG ... Classification #Allergy
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... hours - Examples: Anaphylaxis ... Hay fever, Food allergies ... , Drug allergies ... #allergy #table
Effects of H1 Antihistamines at Histamine, Adrenergic, Cholinergic, and Serotonin-Binding Receptors
Cholinergic - Incr Dry mouth, Incr
Effects of H1 Antihistamines ... Appetite Histamine H1 ... - Decr Allergic ... Incr Appetite #H1
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Type IV Hypersensitivity ... mediated; exposure to allergen ... Allergic reaction ... Initial exposure to allergen ... ivy) #TypeIV #Type4