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Drug Treatment of Anaphylaxis and Allergic Reactions First-Line Therapy - Epinephrine - Oxygen -
Anaphylaxis and Allergic ... Second-Line Therapy - H1 ... #Medications #Allergy
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... Ex: Antibiotic allergies ... fever, Urticaria, Allergic ... #Allergic #Reactions ... Classification #Diagnosis
Effects of H1 Antihistamines at Histamine, Adrenergic, Cholinergic, and Serotonin-Binding Receptors Cholinergic - Incr Dry mouth, Incr
Effects of H1 Antihistamines ... Appetite Histamine H1 ... - Decr Allergic ... Incr Appetite #H1
Medications Used in Allergic Rhinitis - Mast Cell Stabilizers - H1-antagonists - α-Sympathomimetics #Allergic #Rhinitis #medications #pharmacology
Medications Used in Allergic ... Stabilizers - H1 ... α-Sympathomimetics #Allergic
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... causes development ... of allergen-specific ... Allergic reaction ... Initial exposure to allergen
Angioedema - Classification Diagnosis and Treatment Types of Angioedema: • Acute allergic angioedema - Usually occurs with
Classification Diagnosis ... Angioedema: • Acute allergic ... exposure • Non-allergic ... cell-mediated in > 90% of cases ... Classification #Types #Diagnosis
Eosinophils (Eos) and hypereosinophilia (HE) Caused by eosinophilopoietic cytokines Common causes: - Drug reaction - Helminth infection -
cytokines Common causes ... infection - Allergic ... + T cells) - Allergic ... #Differential #Diagnosis ... #Causes
Allergic Reaction Classification Type 1 reaction: Acute anaphylactic reaction Type 2 reaction: Cytotoxic reaction Type 3 reaction: Immune complex Type
Allergic Reaction ... delayed reaction #Allergic ... Classification #Types #allergy ... #diagnosis
Management of Anaphylaxis - Interventions Epinephrine - Bolus, Infusion, Nebulized Posture O2 Fluids Albuterol H1-Antihistamines, H2-Antihistamines Glucocorticoids Additional Vasopressor Glucagon Sugammadex Methylene blue Tranexamic acid ECMO #anaphylaxis #management #treatment
Fluids Albuterol H1 ... Interventions #allergy
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... - Differential Diagnosis ... ): - Allergic ... #Differential #Diagnosis ... #Causes #hematology
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