14 results
Rheumatoid Arthritis
Rheumatoid Arthritis (RA) is an inflammatory autoimmune condition. While chiefly thought of as a joint
Rheumatoid Arthritis ... disorder, RA has ... systemic nature of RA sees ... #msk #arthritis ... #TNF #CRP #RANKL
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
coagulopathy, tumor ... that patient had ... Like in this case ... - parvovirus, HIV ... #Joint #Pain #MSK
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
in Rheumatoid arthritis ... markers (CRP, ESR ... inflammation that seeps ... affects the knee hip ... Comparison #Versus #MSK
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... common sites: hip ... , shoulder ... Osteomyelitis / Septic Arthritis ... pain w elevated CRP
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... Fever/Chills/Joint ... - Inflammatory ... differential #diagnosis #msk ... #physicalexam
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gout (Gouty Arthritis ... ) - MSK Radiology ... • This case should ... diagnosis: • Inflammatory ... PVNS/Giant Cell Tumor
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
axial (spine, shoulders ... , hips)? ... weeks) Can Be Caused ... Parvovirus B19 • HIV ... #Diagnosis #MSK
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
of the affected joint ... ANAs RF test should ... antibody testing has ... Additional tests: HIV ... • Sacroiliac joint
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
disease of unknown cause ... , and hip muscle ... for giant cell arteritis ... C-reactive protein (CRP ... and long head biceps
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
and biologics (tumor ... attraction of various inflammatory ... insufficiency - Joints ... Arthralgia's (common), arthritis ... and ankles) #HSP