14 results
Rheumatoid Arthritis
Rheumatoid Arthritis (RA) is an inflammatory autoimmune condition. While chiefly thought of as a joint
Arthritis (RA) is an inflammatory ... disorder, RA has ... systemic nature of RA sees ... #msk #arthritis ... #TNF #CRP #RANKL
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... coagulopathy, tumor ... that patient had ... Like in this case ... #Joint #Pain #MSK
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
markers (CRP, ESR ... inflammation that seeps ... affects the knee hip ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... common sites: hip ... , shoulder ... pain w elevated CRP ... #differential #diagnosis
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gouty Arthritis) - MSK ... with joint-space ... • This case should ... : • Inflammatory ... PVNS/Giant Cell Tumor
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential Diagnosis ... Fever/Chills/Joint ... - Giant cell tumor ... #msk #physicalexam
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... axial (spine, shoulders ... , hips)? ... weeks) Can Be Caused ... #MSK #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
ANAs RF test should ... antibody testing has ... Additional tests: HIV ... (to support a diagnosis ... laboratory #workup #diagnosis
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
disease of unknown cause ... , and hip muscle ... and hips ... C-reactive protein (CRP ... and long head biceps
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
and biologics (tumor ... attraction of various inflammatory ... insufficiency - Joints ... and ankles) #HSP ... Pathophysiology #Diagnosis