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diagnosis anemia chemotherapy cyp3a4 doac inducers inhibitors interactions management mds myelodysplasia myelodysplastic pglycoprotein syndromes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... - β-lactam antibiotics ... anemia Treatment ... #Anemia #oncology ... #hematology #diagnosis
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
interactions) Cancer-treatment ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Causes • Anemia • Aplastic ... isoniazid) • Antibiotics ... factors (examples: G-CSF ... Syndromes #diagnosis #hematology ... #oncology
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