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diagnosis management kshv neurology rheumatology ddx id idfellowcase syndrome classification cytokine hemophagocytic hlh iris lymphohistiocytosis lymphoproliferative manifestations myelitis neurological reconstitution
Kaposi Sarcoma Herpes Virus (KSHV) By Dr. Sara Dong @swinndong via #IDFellowCase #ID #Infectious Diseases #Infections #Differential
Kaposi Sarcoma Herpes ... IDFellowCase #ID #Infectious ... Diseases #Infections ... #Differential # ... Diagnosis #KSHV #HHV
KSHV Inflammatory Cytokine Syndrome (KICS) By Dr. Sara Dong @swinndong via #IDFellowCase #ID #Infectious Diseases
KSHV Inflammatory ... IDFellowCase #ID #Infectious ... Diseases #Infections ... Diagnosis #KSHV #HHV ... #KICS #Kaposi
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... Acquired HLH: • Infections ... Virus (EBV, CMV, HHV8 ... Still disease, Infection ... Etiological+++: Anti-infectious
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Infectious: Brain ... Myeloma/amyloid • Infectious ... Polymyositis • Immune ... amiodarone, Alcohol • Infections
KSHV Inflammatory Cytokine Syndrome (KICS) Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
KSHV Inflammatory ... if present Infectious ... #KSHV #Inflammatory ... Cytokine #Syndrome #Kaposi ... diagnosis #management #hhv8
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
to an existing infection ... opportunistic infection ... an unrecognized infection ... drug-resistant infection ... , HHV8 - Worsening
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... Necrotizing, pauci-immune ... respiratory tracts Immune ... Syndrome: - Ocular inflammatory ... to exclude are infections
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... to exclude are infections ... Recurrent middle ear infections ... , recent viral infection ... syndrome: Ocular inflammatory
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Reconstitution Inflammatory ... (IRIS): • In HIV ... Meningitis • Include: vasculitis ... and not direct infection ... Tuberculosis #diagnosis #differential
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
etiology unknown • Infectious ... Direct microbial infection ... cells: consider infectious ... be ordered • Infectious ... disorders • Infections
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