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diagnosis tuberculosis activetb latenttb aids cns fungal manifestations mycobacteria mycoses myelitis neurological nontuberculous opportunistic reconstitution syndrome transverse
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
infection • Pulmonary ... (NTM) • Fungal ... • HIV: 2/3 pulmonary ... pneumothorax, bronchiectasis ... #Diagnosis #Management
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
infection • Pulmonary ... (NTM) • Fungal ... • HIV: 2/3 pulmonary ... pneumothorax, bronchiectasis ... #Diagnosis #Management
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... lung infections ... • Primarily occurs ... Pulmonary Disease ... #Infections #differential
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
• A state of hyperinflammatory ... worsening of that disease ... fevers • MAC/NTM ... #IRIS #Immune ... #Diagnosis #Management
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
injury → mucous stasis ... : TB, NTM, PNA ... • Primary ciliary ... , CCP, ANCA • HIV ... #pulmonary #differential
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
lesion Pott's Disease ... Syndrome (IRIS) ... : • In HIV+, usually ... stage) • Headache ... #TB #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... reactivation of latent ... Antimicrobial treatment ... required until immune ... altered mental status
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Hyperreflexia develops later ... simplex virus, HIV ... , Hep A/B/CMV, TB ... #neurology #differential
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
iron overload states ... pulmonary infection ... antigen testing ... , ocular, or disseminated ... Fungal #Diagnosis #Management
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