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differential tuberculosis activetb latenttb aids cns fungal manifestations mycoses myelitis neurological nontuberculous ntm opportunistic reconstitution syndrome transverse
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
infection • Pulmonary ... • HIV: 2/3 pulmonary ... characteristic features Clinical ... pneumothorax, bronchiectasis ... #Diagnosis #Management
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
infection • Pulmonary ... • HIV: 2/3 pulmonary ... characteristic features Clinical ... pneumothorax, bronchiectasis ... #Diagnosis #Management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
• A state of hyperinflammatory ... worsening of that disease ... organizing PNA • Mycobacterium ... #IRIS #Immune ... #Management
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Centrilobular nodules - Bronchiectasis ... Kansasii: • Mimics TB ... • Primarily occurs ... Disease: Clinical ... #infectiousdiseases
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
injury → mucous stasis ... : TB, NTM, PNA ... • Primary ciliary ... , CCP, ANCA • HIV ... Treatment:
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
lesion Pott's Disease ... Syndrome (IRIS) ... : • In HIV+, usually ... the tuberculoma (later ... stage) • Headache
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
reactivation of latent ... should be based on clinical ... Antimicrobial treatment ... required until immune ... altered mental status
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Hyperreflexia develops later ... simplex virus, HIV ... , Hep A/B/CMV, TB ... #management #neurology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
iron overload states ... pulmonary infection ... antigen testing ... , ocular, or disseminated ... #Management #Infections
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