13 results
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... Blood Work: - ... Hypokalemia - Hypomagnesemia ... dominant kidney disease ... #Workup #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
be treated with IV ... losses: • High Blood ... , Gitelman syndrome ... diagnosis #Algorithm #differential ... #potassium #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... Normal or low blood ... ratio 0.5%) Differential ... • Autoimmune disease ... #nephrology #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... plateletcount), peripheral blood ... testing - Lab ... (CVID, WAS), (neurologic ... #hematology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Crush injury • Blood ... - Tumor lysis syndrome ... • Addison’s disease ... potassium #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Crush injury • Blood ... - Tumor lysis syndrome ... • Addison’s disease ... potassium #high #nephrology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
: Fever, flank pain ... • Hypocalcemia ... , Hyperkalemia: ... false negatives on testing ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Crossmatch - involves testing ... : Fever, flank pain ... - Hypocalcemia ... , Hyperkalemia: ... diagnosis #management #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Infection - Viral (HIV ... UA positive for blood ... of underlying disease ... causes #treatment #nephrology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Mycoplasma, EBV, HIV ... younger pts) Differential ... chills, flank pain ... hemolytic #anemia #hematology