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oncology blood product reactions chronic classification cll common cvid gap globulin hodgkins hypogammaglobulinemia immunodeficiency leukemia lymphocytic lymphoma mds myelodysplasia myelodysplastic
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Platelet Disorders ... Diagnosis and Workup ... Risks factor for HIV ... Diagnosis #Causes ... #Workup #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- CMV - HCV ... - HIV • Immune ... immunodeficiency virus (HIV ... anemia Treatment ... #hematology #diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... • HCV, HBV Not ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... hemolytic anemia ... DDX - Other causes ... Epstein-Barr syndrome, HIV ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Anemia • Aplastic ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... , thrombocytopenia ... Pure red cell aplasia ... #workup #oncology ... #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... infections (acute HIV ... , HBV, EBV, VZV, ... gastric tumors • Hematology ... #diagnosis #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
due to marrow aplasia ... Extremely rare - HIV ... 2,000,000,000, HBV ... in 100,000,000, HCV ... #management #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Hodgkin Lymphoma Workup ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
due to marrow aplasia ... Extremely rare - HIV ... 2,000,000,000, HBV ... in 100,000,000, HCV ... #management #hematology
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