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blood oncology product aplastic common cvid disorders extravascular hemolytic hodgkins hypogammaglobulinemia immunodeficiency immunology intravascular nonpalpable palpable platelet purpura transfusion transfusions
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... Diagnosis and Workup ... Risks factor for HIV ... #Diagnosis #Causes ... #Workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation ... microangiopathy: Thrombotic thrombocytopenic ... e.g. lupus, CLL, lymphoma ... #differential # ... diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
anemia - Splenomegaly ... • HCV, HBV Not ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- CMV - HCV ... - HIV • Immune ... immunodeficiency virus (HIV ... #oncology #hematology ... #diagnosis #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
severe thrombocytopenia ... Extremely rare - HIV ... 2,000,000,000, HBV ... in 100,000,000, HCV ... #management #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Workup: • Full ... Treatment • Early ... #diagnosis #classification ... #hematology #oncology ... #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
severe thrombocytopenia ... Extremely rare - HIV ... 2,000,000,000, HBV ... in 100,000,000, HCV ... #management #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
hemolytic anemia ... DDX - Other causes ... Epstein-Barr syndrome, HIV ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
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