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differential arthritis hodgkins lymphocytic lymphoma approach comparison erythematosus gap globulin hemeonc laboratory lupus mds myelodysplasia myelodysplastic nonhodgkins paraproteinemias protein proteingap
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... , fever, joint pain ... #Hematology #Oncology ... #Diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Immunosuppression (e.g., HIV ... - Infections (HIV ... , EN, HTLV-1, HCV ... Tuberculosis • HIV ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... • Neutropenia, anemia ... #CLL #Chronic ... #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... fludarabine) 3) Monoclonal ... #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... - parvovirus, HIV ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Zone Lymphoma (HCV ... ) • CLL & MBL ... et diutinum Neurologic ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... infections (acute HIV ... , HBV, EBV, VZV, ... gastric tumors • Hematology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... Cell Leukemia ... Myeloproliferative Disease ... #diagnosis #hematology ... #oncology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Additional tests: HIV ... , and low back pain ... #Disease #Rheumatoid ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... pain • Swan neck ... with Lupus: • Chronic ... Hodgkin lymphoma and leukemia ... #Rheumatology
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